Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - 5-HT Receptor - SB 258585 hydrochloride

SB 258585 hydrochloride

CAS No. 1216468-02-8

SB 258585 hydrochloride( SB258585 )

Catalog No. M10810 CAS No. 1216468-02-8

SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SB 258585 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM.
  • Description
    SB-258585 is a potent, selective and orally active 5-HT6 receptor antagonist with Ki of 8.9 nM, >160-fold selectivity over other 5-HT receptor subtypes; also is an inhibitor of HCV entry in liver-derived cell lines as well as primary hepatocytes, modulates localization of the coreceptor tight junction protein claudin-1 (CLDN1) in a 5-HT6-independent manner, induces intracellular accumulation of CLDN1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SB258585
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1216468-02-8
  • Formula Weight
    523.814
  • Molecular Formula
    C18H23ClIN3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (238.63 mM)
  • SMILES
    CN1CCN(CC1)C2=C(C=CC(=C2)NS(=O)(=O)C3=CC=C(C=C3)I)OC.Cl
  • Chemical Name
    4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hirst WD, et al. Br J Pharmacol. 2000 Aug;130(7):1597-605. 2. Riva L, et al. J Virol. 2018 Apr 27;92(10). pii: e01982-17.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Perospirone hydrochl...

    Perospirone hydrochloride is an atypical antipsychotic agent for the treatment of schizophrenia. ?It also displays affinity towards 5HT1A receptors as a partial agonist.

  • p-MPPI hydrochloride

    p-MPPI hydrochloride is a selective antagonist of 5-HT1A receptor, and has antidepressant and anxiolytic-like effects.

  • glucosylvitexin

    Glucosylvitexin inhibits TPO activity.

Sign In Join Free